Epidermodysplasia verruciformis is an extremely rare disorder that makes people prone to widespread human papillomavirus (HPV) infection. This infection causes scaly macules and papules (cutaneous squamous cell carcinomas) to grow on the hands, feet, and even face.
These
skin “eruptions” appear as wart-like lesions — and even wood-like and
horn-like growths — with reddish-brown pigmented plaques.
Typically, the skin tumors start to emerge in people between the age of
20 and 40, and the growths tend to appear on areas exposed to the sun.
Also called Lewandowsky-Lutz dysplasia, there is no known cure, though
treatments to scale back the growths are possible.
The
disorder was brought to the public’s attention in November 2007 when a
video of a 34-year-old Indonesian man named Dede Koswara appeared on the internet. In 2008, he underwent surgery to have 13 pounds (6 kg) of the warts removed.
After the lesions and horns were extracted from his hands, head, torso,
and feet, his hands were grafted with new skin. In all, about 95% of
the warts were removed.
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